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Jennifer Lopez, David Guetta Team Up for Anthemic Single ‘Save Me Tonight’

Lopez will livestream a performance of the track as she kicks off the second phrase of her Las Vegas residency this evening

Jennifer Lopez, David Guetta Team Up for Anthemic Single ‘Save Me Tonight’

David Guetta and Jennifer Lopez

Courtesy of Warner Records
Emily Zemler
By Emily ZemlerMar 06, 2026
Emily Zemler
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Jennifer Lopez and David Guetta released a collaborative single, “Save Me Tonight.” Lopez initially teased the anthemic, dance-ready track during World Pride Music Festival last summer, as well as on her Up All Night: Live in 2025 tour.

The song marks Lopez’s first new release since the Kiss of the Spider Woman soundtrack dropped last year. The singer will give the track its official global live debut tonight when she kicks off the next phase of her Las Vegas residency at the Colosseum. The performance will be simulcast on her TikTok Live, Instagram Live, and YouTube Live channels.

- YouTube youtu.be

Lopez initially launched her stint in Vegas in December. The shows featured her performing a variety of her own music, including hits like “Jenny From the Block” and “Let’s Get Loud.” On opening night she also welcomed Ja Rule to the stage for two songs, “Ain’t It Funny” and “I’m Real.” The new phase of concerts will run through March 28.

The residency shows are the first live concert performances Lopez scheduled since cancelling her This Is Me… Live tour in 2024. “I am completely heartsick and devastated about letting you down,” she said at the time. “Please know that I wouldn’t do this if I didn’t feel that it was absolutely necessary. I promise I will make it up to you and we will all be together again. I love you all so much. Until next time…”

Guetta has recently collaborated with artists like Sia and Teddy Swims. The DJ spoke to Rolling Stone about his success in January, saying he has a “pure love for what I do.”

“I crave challenges, stepping out of my comfort zone, taking risks, questioning myself,” Guetta said. “Being on stage is a drug. In Ibiza, I’ll work on music in the morning, then test a track that same night in front of thousands. Nothing beats watching a crowd lose it to an idea born just hours earlier.”

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